課程資訊
課程名稱
碩士班專題討論
Seminar (m.s) 
開課學期
103-1 
授課對象
生命科學院  分子與細胞生物學研究所  
授課教師
董桂書 
課號
MCB7001 
課程識別碼
B43 M0020 
班次
 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一6,7(13:20~15:10) 
上課地點
生科4C 
備註
與黃火鍊、王致恬合開
總人數上限:40人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1031MCB7001_ 
課程簡介影片
 
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課程概述

1.安排校內外教師專題演講
2.每位同學選擇分子與細胞生物學重要文獻做專題報告,並與教師和同學討論
 

課程目標
訓練同學使其具備文獻閱讀、組織、報告和討論的基本能力 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
9/15  圖書館介紹/organization 
第2週
9/22  about presentation 
第3週
9/29  paper study 
第4週
10/06  舒玟綺Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related
disease (in nondiabetics)

<br> 陳品君Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. 
第5週
10/13  郭仲軒FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging <br> 劉士元Oxytocin is an age-specific circulating hormone
that is necessary for muscle maintenance and
regeneration <br>吳亭諭Resveratrol ameliorates aging-related
metabolic phenotypes by inhibiting
cAMP phosphodiesterases 
第6週
10/20  Dr. Sean Megason<br> 陳侑頡Sirt1 extends life span and delays aging in mice through the regulation of nk2 homeobox 1 in the DMH and LH<br> 嚴家鴻A Genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel

 
第7週
10/27  連柏翰Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
<br>
吳志昊Protein aggregation in E. coli : short term and long
term effects of nutrient density <br>
洪子喬Phenotypic Plasticity and Effects of Selection on Cell
Division Symmetry in Escherichia coli 
第8週
11/03  陳宜佩Steroid hormone signalling links reproduction to
lifespan in dietary-restricted Caenorhabditis elegans<br> 吳美萱The Intrinsic Apoptosis Pathway Mediates
the Pro-Longevity Response to
Mitochondrial ROS in C. elegans 
第9週
11/10  王柏鈞MicroRNAs Mediate Dietary-Restriction-Induced Longevity through PHA-4/FOXA and SKN-1/Nrf Transcription Factors
<br>蔡佳均Astaxanthin protects ARPE-19 cells from oxidative stress via upregulation of Nrf2-regulated phase II enzymes through activation of PI3K/Akt 
第10週
11/17  許瓊方 P44, the longevity-assurance isoform of P53, regulates tau<br> 謝巧慧Chronic inflammation induces telomere
dysfunction and accelerates ageing in mice <br>侯君里Cytokine expression and signaling in drug-induced cellular senescence 
第11週
11/24  陳韋安Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging
<br> 汪健州Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells
 
第12週
12/01  Dr. Meyer B. Jackson <br>
陳育岷Intertissue Control of the Nucleolus via a Myokine-Dependent Longevity Pathway<br> 陳湘鈞YAP/TEAD–mediated transcription controls cellular
senescence
 
第13週
12/08  謝伯思Rapamycin suppresses brain aging in senescence&#8208;accelerated OXYS
rats<br> 張佑群Enhanced fitness of adult spermatogonial stem cells bearing a paternal
age-associated FGFR2 mutation 
第14週
12/15  蔡雅因 Adaptive capacity to bacterial diet
modulates aging in C. elegans <br> 莊 欽Life-span extension by a metacaspase
in the yeast Saccharomyces cerevisiae<br> 蔡岳宏Drosophila life span and physiology
are modulated by sexual
perception and reward
 
第15週
12/22  黃亭穎Inhibition of x-box binding protein 1 reduces tunicamycininduced
apoptosis in aged murine macrophages<br> 蔡宛育Replication stress is a potent driver of functional
decline in ageing haematopoietic stem cells<br> 許明倩Resveratrol modulates mitochondria dynamics in
replicative senescent yeast cells 
第16週
12/29  鄧瑾瑜 Increased mitochondrial biogenesis preserves intestinal stem cell
homeostasis and contributes to longevity in Indy mutant flies <br>郁 芸p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice<br> 徐嘉偉